Synthesis of .GAMMA.-oryzanol (triterpenyl esters of ferulic acid)-14C.
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The effect of trans-ferulic acid and gamma-oryzanol on ethanol-induced liver injury in C57BL mouse.
The effects of the oral administration of trans-ferulic acid and gamma-oryzanol (mixture of steryl ferulates) with ethanol (5.0 g per kg) for 30 days to c57BL mice on ethanol-induced liver injury were investigated. Preventions of ethanol-induced liver injury by trans-ferulic acid and gamma-oryzanol were reflected by markedly decreased serum activities of plasma aspartate aminotransferase, alani...
متن کاملSubstituted Caffeic and Ferulic Acid Phenethyl Esters: Synthesis, Leukotrienes Biosynthesis Inhibition, and Cytotoxic Activity.
Glioblastoma multiforme (GBM) is an aggressive brain tumor that correlates with short patient survival and for which therapeutic options are limited. Polyphenolic compounds, including caffeic acid phenethyl ester (CAPE, 1a), have been investigated for their anticancer properties in several types of cancer. To further explore these properties in brain cancer cells, a series of caffeic and feruli...
متن کاملFerulic acid sugar esters are recovered in rat plasma and urine mainly as the sulfoglucuronide of ferulic acid.
Ferulic acid sugar esters, the common form of ferulic acid (FA) in cereals, show a stronger antioxidant potential than FA in vitro. However, there is little information on their metabolism and excretion in vivo. In the present study, we investigated the metabolic derivatives of FA in the plasma, urine and feces of rats administered 70 micro mol/kg body of 5-O-feruloyl-L-arabinofuranose (FAA), f...
متن کاملSynthesis, Evaluation of Anticancer Activity and QSAR Study of Heterocyclic Esters of Caffeic Acid
Caffeic acid phenethyl ester(CAPE) suppresses the growth of transformed cells such as human breast cancer cells, hepatocarcinoma , myeloid leukemia, colorectal cancer cells, fibrosarcoma, glioma and melanoma. A group of heterocyclic esters of caffeic acid was synthesized using Mitsunobu reaction and the esters were subjected to further structural modification by electrooxidation of the catecho...
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ژورنال
عنوان ژورنال: RADIOISOTOPES
سال: 1981
ISSN: 1884-4111,0033-8303
DOI: 10.3769/radioisotopes.30.3_156